The biomechanics of atherosclerosis development
Keywords:
aorta, blood viscosity, bifurcation study, atherosclerosis developmentAbstract
In this paper, we investigate the bio-mechanics of atherosclerosis development in human physiology. Blood is modelled as an incompressible fluid of variable viscosity flowing in a slightly diverging channel (i.e. large artery) of small aspect ratio [15]. The hypothetical viewpoint in this work is the existence of relationship between the atherosclerosis development, blood viscosity, flow separation and turning points in the flow field. The problem is tackled by asymptotic approximation and the graphical results are discussed quantitatively.
References
[l] G.A. Baker Jr. Essentials of Padé Approximants. Academic Press, New York, 1975.
[2] G.K. Batchelor. An Introduction to Fluid Dynamics. Cambridge University Press, 1967.
[3J H. Blasius. Laminare Stromung in Kanalen wechselnder Breite. Z. Math. Phys., 58: 225- 233, 1910. 31
[4] J .C.F. Chow, K. Soda. Laminar flow and blood oxygenation in channels with boundary irregularities. J. Appl. Mech. (Trans . ASME), 40: 843, 1973.
[5] P.G. Drazin. Nonlinear Systems. Cambridge University Press, 1992.
[2] G.K. Batchelor. An Introduction to Fluid Dynamics. Cambridge University Press, 1967.
[3J H. Blasius. Laminare Stromung in Kanalen wechselnder Breite. Z. Math. Phys., 58: 225- 233, 1910. 31
[4] J .C.F. Chow, K. Soda. Laminar flow and blood oxygenation in channels with boundary irregularities. J. Appl. Mech. (Trans . ASME), 40: 843, 1973.
[5] P.G. Drazin. Nonlinear Systems. Cambridge University Press, 1992.
Published
2023-02-02
Issue
pp. 23-31
Section
Articles
License
Copyright © The Author(s).
This work is licensed under the Creative Commons Attribution 4.0 International CC BY 4.0.
How to Cite
Makinde, O. D., Acho, T. M., Sibanda, P., & Lungu, E. M. (2023). The biomechanics of atherosclerosis development. Computer Assisted Methods in Engineering and Science, 10(1), 23-31. https://cames3.ippt.pan.pl/index.php/cames/article/view/1100
